RESEARCH
FOR CINNAMON

The millennia of tradition and experience of the positive health effects of cinnamon are now confirmed by science, this alone is the largest “clinical study” ever done. The MHCP substance in cinnamon has a positive effect on sugar balance and makes LOSEBIG an even more powerful aid in your efforts.

CANELA

The famous MHCP of cinnamon at LOSEBIG

WHAT IS MHCP

Cinnamon contains the active substance MHCP a hydroxychalcone which acts as a mimetic for insulin in 3T3-L1 adipocytes, i.e. it has insulinomimetic action.

Taking MHCP stimulates glucose uptake and glycogen synthesis at a similar level to insulin. In a study conducted, glycogen synthesis was inhibited by both bortmannin and LY294002, anti-PI-3-kinase inhibitors. In addition, MHCP treatment activated glycogen synthesis and inhibited glycogen kinase-3-beta synthesis activities, known effects of insulin treatment. Insulin receptor analysis showed that the receptor was phosphorylated upon exposure to MHCP. This implies that insulin flux was activated by MHCP.

Along with the comparison of MHCP with insulin, experiments with MHCP and insulin combined were performed. The responses observed using the dual treatment were greater than the additive treatment, indicating synergy between the two compounds.

Together, these results demonstrate that cinnamon MHCP is an effective insulin mimetic. MHCP may be useful in the function of insulin resistance.

Investigations: