The bodyguards
of LOSEBIG
In addition to the chromium, the rest of the well studied flavors, the avocado and the unique French Lilac – the source of the miraculous metformin, all ingredients that we have reported on extensively, Losebig also contains additional important factors that provide even greater effectiveness. The so-called bodyguards.
Eggplant extract
The effective eggplant extract in the composition of LOSEBIG, against obesity!
The eggplant extract in Loosebig (purple eggplant) is an excellent source of chlorogenic acid, a phytochemical that has been shown to have anti-obesity properties while its other phytochemicals can help increase serotonin and make the body reduce cravings. At the same time anthocyanins, the polyphenols that give them their purple color have been classified as micronutrients that help balance blood glucose, resulting in the relief of binge eating episodes.
Sources
LOSEBIG & TYROSHINE
L-Tyrosine is an important amino acid for the human body.
It is essential for the production of important neurotransmitters, such as dopamine, norepinephrine and epinephrine, which regulate mood, memory and energy. Losebig Spray’s tyrosine is a precursor to the above substances and is a good supplement choice for those trying to lose weight because, in theory, it can help speed up metabolism.
Contribution to the function of the thyroid gland: Controls our body’s metabolism and energy.
NAD, GERANSE & PAHYSARCY
What is NAD and how does it work in LOSEBIG against obesity?
Adenine nicotinamide dinucleotide as a coenzyme, or “helper” molecule as it is called, binds directly to other enzymes and participates in the activation of biochemical reactions at the cellular level. Without it, the human body could not function properly. It has the two dominant roles in the human body, to create energy and to regulate cell function. As an accessory molecule, it directly and indirectly affects many cellular functions, including DNA repair, gene expression and immune function.
NAD levels decrease with age, as the body produces less as it ages. In addition, inflammation, and oxidative stress destroy it in the body. Low NAD is the cause of many age-related problems. Decreasing it, leads to a decrease in healthy cellular metabolism. This, in turn, results in the familiar signs of aging, such as loss of muscle tone, reduced exercise capacity, obesity and weakness.
CANELA
The famous MHCP of cinnamon at LOSEBIG
WHAT IS MHCP
Cinnamon contains the active substance MHCP a hydroxychalcone which acts as a mimetic for insulin in 3T3-L1 adipocytes, i.e. it has insulinomimetic action.
Taking MHCP stimulates glucose uptake and glycogen synthesis at a similar level to insulin. In a study conducted, glycogen synthesis was inhibited by both bortmannin and LY294002, anti-PI-3-kinase inhibitors. In addition, MHCP treatment activated glycogen synthesis and inhibited glycogen kinase-3-beta synthesis activities, known effects of insulin treatment. Insulin receptor analysis showed that the receptor was phosphorylated upon exposure to MHCP. This implies that insulin flux was activated by MHCP.
Along with the comparison of MHCP with insulin, experiments with MHCP and insulin combined were performed. The responses observed using the dual treatment were greater than the additive treatment, indicating synergy between the two compounds.
Together, these results demonstrate that cinnamon MHCP is an effective insulin mimetic. MHCP may be useful in the function of insulin resistance.
The millennia of tradition and experience of the positive health effects of cinnamon are now confirmed by science, this alone is the largest “clinical study” ever done. The MHCP substance in cinnamon has a positive effect on sugar balance and makes LOSEBIG an even more powerful aid in your efforts.
Investigations:
Tryptophan
Why is it so important to LOSEBiG?
Tryptophan is one of the 8 essential amino acids that our body needs for the processing of proteins and the synthesis – production of serotonin (neurotransmitter that causes the feeling of euphoria) and dopamine -to a lesser extent- (neurotransmitter that causes feelings of pleasure, good mood and at the same time “activates” us.
So if you feel nervousness, tension and anxiety or have a “bad” mood and do not sleep well or are faced with depression, then tryptophan is the solution you are looking for!
Weight gain: Decreased levels of tryptophan and serotonin correlate with increased consumption of carbohydrate foods. Also manifested is the mood for snacking and hyperphasic episodes. Tryptophan controls bulimia and regulates appetite levels.
Oat extract
Oat extract in LOSEBIG and the recent findings!
The onset of obesity has been largely associated with appetite-regulating hormones that control, regulate and suppress hunger, satiety or energy consumption.
Many research and clinical studies show that oats have a positive effect on anthropometric measures such as BMI, waist circumference, waist-to-hip ratio, lipid profile, total cholesterol, weight, appetite and blood pressure.
Many studies suggest that oats are rich in protein, fiber, healthy fats, Fe, Zn, Mg, Mn, free phenols, beta-glucan, ferulic acid, aventhramides and many other beneficial ingredients.
Beta glucan is the most important bioactive ingredient that lowers cholesterol levels and supports the body’s defense system to prevent infections. Therefore, several clinical studies have supported the use of oats against obesity, appetite hormones and energy regulation.
Investigations:
GARCINIA/HCA EXTRACT
The relationship of the efficacy of LOSEBIG and GARCINIA/HCA.
The aim of this systematic review is to examine the efficacy of Garcinia extract, hydroxycitric acid (HCA) as a weight reduction agent, using data from randomized clinical trials (RCTs).
Two independent reviewers extracted the data and assessed the methodological quality of the included studies. Twenty-three eligible trials were identified and twelve were included. Nine trials provided data suitable for statistical pooling. Meta-analysis revealed a small, statistically significant difference in weight loss favoring HCA versus placebo (MD: -0.88 kg; 95% CI: -1.75, -0.00). Gastrointestinal adverse events were twice as common in the HCA group compared with placebo in one included study.
It is concluded that RCTs suggest that Garcinia/HCA extracts can cause short-term weight loss.
Investigations:
The composition of LOSEBiG, its use and method of use is a worldwide & registered patent
The study concerning Losebig is the one done by the HELLENIC DIATROPHOLOGICAL SOCIETY – ELDE under Dr. Dimitris Gregorakis. See here the pre-publication of the survey results.
Patent No : 20240100787
*The health claims listed are for the ingredients and are derived from official studies. The company states that the above studies do not relate to its product, but to the ingredients that make up the product.
